Cellular pathology 2 Essay Example | Topics and Well Written Essays - 750 words

Cellular pathology 2 - Essay Example The fibrous strands of the fat have indications of small capillaries. The cancerous cells have a nucleus that is larger than a normal cell. The nucleoli of the cells remain prominent and the cytoplasm is intensely colored with pale sports in some regions at the cellular edges (Baba and CÃ ¢toi, 2007). From the description of the above features, the tumor is slightly progressed with features of cellular alterations reaching the deeper subcutaneous tissue and involves other soft tissues including the skin. Normally, malignant soft tissue tumors display a wide range of behaviors. Histopathology is key in the grading and differentiation of these tumors. Some of the parameters that are used in the grading of these tumors include necrosis, histological type, mitotic activity, tumor differentiation, vascular invasion, cellularity and nuclear pleomorphic. In the histo-pathological parameter, grading is done where tumor necrosis is not the defining element of the tumor. In subtype one; epithelioid hemangio-endethelioma, myxoid liposarcoma, well-differentiated liposarcoma and infantile fibrosarcoma make the list in this category. The histological type with mitosis differentiation follows this type. In this category, well-differentiated leiomyosarcoma with less than six mitosis/ 10 HPF are evident. All the above types of tumor categories are included in this stage if their mitotic differentiation is more than six per 10 HPF. In histopathology type 2, there is evidence of necrosis. All tumors that are obviously not in grade three because of the lesser than 15 percent necrosis. In the third grade of the histopathology classification, the necrosis percentage of the tumor tissue is more than fifteen. This is the final stage of the tumor cell. According to this classification, the tumor cells under examination appear to be in the third staging of the histopathological classification described